TABLE 1

Characterization of eye phenotypes in P35 Pax6132-14Neu mutant mice

Eye class (%)b
Genotypea0Minor iris abnormalities255075100Extreme microphthalmia
+/+118
+/−38190284
−/−32
  • a +/+ were wild-type strain C3H mice; +/− mice were produced in the cross −/− × +/+; −/− mice were from the cross −/− × −/−.

  • b Classes 0, 25, 50, 75, and 100% denote lens/corneal opacities affecting 0, 25, 50, 75 or 100% of the eye, respectively.