TABLE 2

pGAL4 insertions and behavioral phenotypes

Name of insertionBehavioral phenotypesAssociated geneCellular function
2-10↑ ESPQBP-1, 32 bp 5′ of exon 1Poly(Q) tract binding protein (Yoshimura et al. 2006)
3-54↓ PM, ↑ OMtribbles (trbl), ∼250 bp 5′ of exon 1Protein degradation regulation (Mata et al. 2000; Rorth et al. 2000)
3-68↑ ESCG31886, exon 1Unknown
4-43NormalTetraspanin at 42El ∼35 bp 5′ of exon 1Ectoderm and nervous development (Grumbling and Strelets 2006)
5-103↑ ESCG33472, 3′ end of predicted geneUnknown
5-120Normalscabrous (sca), ∼125 bp 5′ of exon 1Development of nervous system, eyes, sensory bristles, and wings (Powell et al. 2001)
8-47Normalpathetic (path), intron 1 of transcript AAmino acid transporter (Goberdhan et al. 2005)
9-220↑ ESBetween
(1) l(2)0128, ∼100 bp 5′ of exon 1 andl(2)01289: electron transport (Grumbling and Strelets 2006)
(2) putative homeodomain transcription factor (phtf), ∼1 Kbp 5′ of exon 1phtf: putative homeodomain transcription factor (Manuel et al. 2000)
10-110↑ ES, ↓ OMCG2185, exon 1Ca2+-binding protein (Grumbling and Strelets 2006)
10-149NormalBetween
(1) Glial Lazarillo (GLaz), ∼1.5 Kbp 5′ of exon 1 andGLaz: Lipocalin gene product (Sanchez et al. 2000)
(2) Serine palmitoyltransferase subunit I (Spt-I), ∼450 bp 5′ of exon 1Spt-I: Lipid metabolism (Grumbling and Strelets 2006)
  • ES, ethanol sensitivity; PM, place memory; OM, olfactory memory.