TABLE 4

HapMap SNPs in exons for which the Neanderthal nucleotide could be determined

NameChrSyn/NonNeanChimHumCeuHcbJptYri
N-derived
rs15739717SynCTC/T0.950.560.70.77
N-ancestral
rs112082991NonTTG/T0.7080.5670.4090.30
rs81925062NonAAG/A0.05000
rs4496436NonGGA/G0.0920.0240.0580.24
rs230482415NonGGA/G0.5250.7220.7160.18
rs170098194SynCCT/C0000.12
  • Name, SNP identifier used by build 36.1 of the HapMap database; Chr, number of human chromosome; Syn, synonymous change; Non, nonsynonymous change; Nean, nucleotide of the Neanderthal; Chim, nucleotide of build 2, version 1 of the chimpanzee reference sequence (pantro2); Hum, pair of nucleotides polymorphic in the HapMap database; Ceu, frequency of the derived nucleotide in the European HapMap database; Hcb, frequency of the derived nucleotide in the Han Chinese HapMap database; Jpt, frequency of the derived nucleotide in the Japanese HapMap database; Yri, frequency of the derived nucleotide in the Yoruban HapMap database. The nucleotide in the chimpanzee sequence is assumed to be ancestral.