TABLE 2

Start and end positions of the estimated QTG interval for four different traits

TraitStartEndWidth
Blindness105,836,061105,879,39643,335
C140.3105,064,982105,165,476100,494
C140.3 spline103,911,000109,239,0005,328,000
C140.10104,725,066105,334,300609,234
C140.10 spline104,200,000107,819,0003,619,000
C140.sli105,006,598105,106,598100,000
C140.sli spline104,107,000108,907,0004,800,000
S140105,128,254105,128,2540
Albinism74,585,04774,651,05466,007
C140.366,064,86283,932,72217,867,860
C140.3 spline71,064,70076,122,6005,057,900
C140.1069,332,64581,775,46612,442,821
C140.10 spline70,585,60076,582,5005,996,900
C140.sli66,031,03481,831,03415,800,000
C140.sli spline70,531,00076,231,0005,700,000
S14066,064,86283,880,10417,815,242
Hepatic fibrosis34,943,32135,021,38778,066
C140.3174,302,841174,330,32527,484
C140.3 spline28,853,50034,625,2005,771,700
C140.1071,459,79471,640,475180,681
C140.10 spline68,479,90071,045,9002,566,000
C140.sli30,278,76030,378,760100,000
C140.sli spline30,278,80033,578,8003,300,000
S14069,346,539173,208,636103,862,097
Cholesterol171,296,339171,297,6021,263
C140.3168,906,046168,913,2077,161
C140.3 spline158,007,000172,090,00014,083,000
C140.10171,920,715172,018,02197,306
C140.10 spline167,094,000171,510,0004,416,000
C140.sli132,907,431133,007,431100,000
C140.sli spline165,907,000172,107,0006,200,000
S14037,310,66437,310,6640
  • “Start” and “End” refer to the actual beginning and end position of the gene. “Width” is the estimated interval, based on applying a cladistic analysis using haplotypes based on 3 SNPs, 10 SNPs, and a length of 100 kb (respectively, C140.3, C140.10, and C140.sli) as well as the estimates after applying a spline to the distribution of P-values (respectively, C140.3 spline, C140.10 spline, and C140.sli spline). The last estimate for each trait (S140) corresponds to a single-marker analysis. Italics indicate estimates that are within 1 Mb of a known regulatory gene.