TABLE 5

Transformations, heritabilities, and common environment effects for 88 phenotypes listed in order of heritability

PhenotypeTransformationCategory% variance due to additive genetic variation (i.e., heritability)% variance due to common environment
%CD8+xPhysiological88.9111.09
CD4+/CD8+x−(1/3)Physiological80.4814.59
Weight, 7 wk (g)x1/3Physiological79.3620.64
Weight, 6 wk (g)x1/3Physiological74.4825.52
%CD4+/CD3+x2Physiological72.7318.48
Weight, 8 wk (g)x1/3Physiological71.9918.29
High density lipoproteins (mmol)xPhysiological69.1117.01
Alkaline phosphatase (units/liter)Embedded ImagePhysiological62.8320.47
Weight, 10 wk (g)x1/3Physiological62.3518.02
%B220+Embedded ImagePhysiological59.8624.66
Glucose 0 (mg/dl)Embedded ImagePhysiological55.3332.08
Red cell distribution widthx−2Physiological55.2912.98
Mean cellular Hb conc. (%)xPhysiological52.1639.97
%CD3+x2Physiological51.3022.51
Ear hole area (mm2)Embedded ImagePhysiological51.0214.46
Mean cellular volume (fl)xPhysiological50.8920.60
Calcium (mmol)xPhysiological48.8931.39
LymphocytesEmbedded ImagePhysiological48.2917.85
Mean corpuscular hemoglobin (pg)xPhysiological47.9420.24
Inspiratory time (metacholine)x−1Physiological44.9610.81
Chloride (mmol)xPhysiological44.7838.43
Open-arm distancex1/3Behavioral42.066.19
%CD4+xPhysiological40.7026.46
Startle responsex1/3Behavioral40.674.20
White blood cell count (n/μl)log10(x + 1)Physiological40.6523.15
Sodium (mmol)xPhysiological39.3437.83
Closed-arm distancexBehavioral38.817.95
Open-arm entriesEmbedded ImageBehavioral38.575.46
Open-arm timeEmbedded ImageBehavioral37.926.08
Enhanced pause (baseline)log10(x)Physiological37.8126.70
Total cholesterol (mmol)xPhysiological37.5017.62
Total beam breaks (30 min)Embedded ImageBehavioral37.1711.14
Respiratory rate (metacholine)log10(x)Physiological36.1312.81
Expiratory time (metacholine)log10(x)Physiological35.0013.94
Glucose 15 (mg/dl)Embedded ImagePhysiological34.8329.86
Total activityxBehavioral33.865.81
Inspiratory time (baseline)x−2Physiological32.7616.55
Alanine transaminase (units/liter)log10(x + 3)Physiological32.2029.18
Respiratory rate (baseline)xPhysiological31.5718.95
Tidal volume (metacholine)x1/3Physiological30.9521.69
Low density lipoproteins (mmol)log10(x)Physiological30.7018.25
Urea (mmol)log10(x + 1)Physiological30.5921.54
Growth slopexPhysiological30.5237.39
Time freezing during cue (sec)xBehavioral30.510.00
Expiratory time (baseline)log10(x)Physiological29.5221.37
Fine movementx2Behavioral29.4510.04
Total beam breaks (first 5 min)Embedded ImageBehavioral29.2712.26
Enhanced pause (metacholine)log10(x)Physiological27.3028.26
Adrenal weightlog10(x)Physiological27.0036.09
Closed-arm timeEmbedded ImageBehavioral26.657.47
Tidal minute volume (metacholine)x1/3Physiological26.5920.01
Albumin (g/liter)xPhysiological26.4222.42
Insulin 30 (ng/ml)x1/4Physiological26.3421.62
Glucose 75 (mg/dl)Embedded ImagePhysiological26.2822.94
Insulin 15 (ng/ml)log10(x)Physiological25.8522.24
Time freezing to context (sec)Embedded ImageBehavioral25.2312.09
PenH differencex1/3Physiological25.2028.85
Platelets (n/μl)xPhysiological25.0719.94
DIRI/DGx1/4Physiological24.6123.89
Triglycerides (mmol)log10(x)Physiological22.5521.94
AUC-IRI/AUC-Gx1/4Physiological22.4822.86
Total beam breaks (last 5 min)Embedded ImageBehavioral22.397.58
Glucose 30 (mg/dl)Embedded ImagePhysiological22.1827.00
% NK cellsx−(1/2)Physiological21.8830.24
DG (mg/dl)xPhysiological21.8224.96
Body length (cm)xPhysiological21.3419.92
AUC-G (mg/dl)xPhysiological21.2424.88
DIRI (ng/ml)x1/3Physiological21.0219.04
Aspartate transaminase (units/liter)x−(1/2)Physiological20.9618.47
AUC-IRI (ng/ml)x1/2Physiological19.2418.87
Closed-arm entriesxBehavioral19.207.00
Tidal volume (baseline)x1/3Physiological18.5625.07
Insulin 0 (ng/ml)log10(x)Physiological17.8326.01
Tidal minute volume (baseline)x1/3Physiological16.5122.21
Phosphorous (mmol)log10(x + 1)Physiological16.1028.41
Insulin slopex1/3Physiological15.216.49
Red blood cell count (n/μl)x3Physiological15.1418.00
Hemoglobin (g/dl)x3Physiological15.1217.83
Time freezing after cue (sec)xBehavioral13.810.00
Change in startle after trainingBlom(x)Behavioral13.614.48
Fecal boliEmbedded ImageBehavioral13.3813.02
Body mass indexxPhysiological13.2114.75
Insulin 75 (ng/ml)x1/3Physiological13.1126.72
Plateletcrit (%)Embedded ImagePhysiological12.9120.24
Hematocrit (%)x3Physiological10.8618.98
Fecal boli after cueEmbedded ImageBehavioral9.916.97
Total protein (g/liter)x2Physiological8.5128.59
K (glucose slope)x1/2Physiological7.6010.28
  • Transformations use the following conventions: x = phenotype; log10, log to base 10; Blom, replace each point with the probit of its relative cumulative frequency.