TABLE 2

Dynamics of the mildly deleterious mutations

NshMfixqHmzHtzIVLequρ
c = 0.2
100.010.01/0.3
0.050.012.9 (0.9)0.065 (0.001)0.018 (0.001)0.093 (0.002)0.16 (0.04)0.39 (0.02)3.30 (0.06)1.47
0.31.6 (1.3)0.035 (0.006)0.009 (0.002)0.053 (0.008)0.04 (0.02)0.28 (0.05)1.94 (0.08)0.89
500.010.0117.1 (3.1)0.258 (0.004)0.108 (0.004)0.299 (0.003)0.07 (0.01)0.32 (0.01)2.64 (0.04)0.84
0.38.3 (3.3)0.194 (0.009)0.075 (0.009)0.238 (0.006)0.02 (0.02)0.23 (0.02)1.94 (0.08)0.71
0.050.010 (0)0.080 (0.001)0.011 (1E-4)0.138 (0.002)0.10 (0.02)0.53 (0.003)4.10 (0.06)1.18
0.30 (0)0.032 (0.001)0.003 (0.001)0.058 (0.002)0.03 (0.01)0.35 (0.01)1.62 (0.05)0.96
1000.010.010 (0)0.242 (0.001)0.078 (0.001)0.328 (0.002)0.07 (0.01)0.44 (0.01)2.48 (0.01)0.90
0.30.02 (0.14)0.173 (0.005)0.048 (0.005)0.249 (0.005)0.02 (0.01)0.29 (0.01)1.73 (0.05)0.79
0.050.010 (0)0.086 (0.001)0.011 (1E-4)0.151 (0.002)0.10 (0.01)0.54 (0.003)4.39 (0.04)1.11
0.30 (0)0.032 (0.001)0.003 (4E-4)0.059 (0.002)0.02 (0.01)0.36 (0.01)1.62 (0.04)0.96
c = 0.7
100.010.01/0.3
0.050.01/0.3
500.010.0127.4 (5.7)0.290 (0.005)0.165 (0.007)0.250 (0.006)0.25 (0.03)0.18 (0.01)2.97 (0.05)0.75
0.323.2 (30.8)0.232 (0.008)0.132 (0.018)0.200 (0.023)−0.04 (0.13)0.14 (0.02)2.37 (0.08)0.59
0.050.010 (0)0.064 (0.001)0.014 (0.0004)0.101 (0.003)0.34 (0.01)0.47 (0.01)3.30 (0.06)1.48
0.30 (0)0.034 (0.001)0.008 (0.001)0.054 (0.001)0.03 (0.04)0.30 (0.01)1.75 (0.04)0.91
1000.010.010.3 (0.6)0.250 (0.004)0.111 (0.006)0.277 (0.004)0.27 (0.05)0.31 (0.02)2.56 (0.04)0.87
0.32.1 (13.9)0.206 (0.002)0.097 (0.02)0.220 (0.01)0.005 (0.10)0.19 (0.03)2.10 (0.20)0.67
0.050.010 (0)0.068 (0.002)0.012 (3E-4)0.111 (0.004)0.28 (0.02)0.50 (0.007)3.48 (0.9)1.39
0.30 (0)0.032 (3E-4)0.005 (3E-4)0.055 (5E-4)−0.004 (0.046)0.34 (0.005)1.64 (0.01)0.97
  • Results are given for simulations with nd = 10 demes and a genomic mutation rate of U = 1 over 1024 loci. Mfix is the number of loci fixed for the deleterious mutant over the whole population. q, Hmz, and Htz are the mean allelic frequency, homozygosity, and heterozygosity, respectively. I is the heterosis, V the mean offspring viability, Lequ the number of lethal equivalents, and ρ the amount of purge (qexp/q). Values in parentheses are standard deviations over 100 replicates. Dashes (—) represent populations that crashed before 2000 generations.