TABLE 4

McDonald-Kreitman tests (coding regions)

FixedPolymorphic
GeneSynonymousNonsynonymousSynonymousNonsynonymousP
bcd 46  7 7 11.00
Bruce 44  4 1 10.19
Gld 58  4 6 10.42
hyd 36  5 0 20.02*
rosy124 3329130.22
sry-alpha 34 34 1 40.36
ade3 68 11 1 01.00
Adh 34 10 2 01.00
amd 42 10 4 11.00
Ddc 49  8 2 40.01**
Eno 28  8 5 11.00
Lam 74 42 4 21.00
Uro 41  8 3 01.00
AnnX 28  3 0 10.13
Gapdh2 26  2 0 0
scute 31 10 2 20.56
sesB 12  3 1 01.00
sisA 38 42 2 60.28
swallow 62 54 1 20.60
Pooled8752987141
  • * P < 0.05,

  • ** P ≤ 0.01.

  • Synonymous and Nonsynonymous are the number of synonymous and nonsynonymous changes, respectively. D. affinis was used as an outgroup. P was calculated using the two-tailed Fisher's exact test, comparing numbers of synonymous vs. replacement changes in the fixed and polymorphic categories, respectively.