TABLE 6

Silent site evolution and modified McDonald-Kreitman test

PolymorphismDivergenced2 × 2 χ2 test
PaUbRcPURP/UP/R
Immunity7816712853741603.59, P = 0.068.21, P < 10-2
Nonimmunity28108353156506.17, P = 0.010.56, P = 0.45
  • a Number of preferred silent mutations.

  • b Number of unpreferred silent mutations.

  • c Number of replacement mutations.

  • d The divergence data are fixations that have been polarized to the D. simulans lineage using the outgroups D. melanogaster and D. yakuba.