G-test of independence for the presence of synonymous and nonsynonymous substitutions in the same codon between D. subobscura and D. pseudoobscura

Codons with one synonymous substitutionCodons without synonymous substitution
Codons with one nonsynonymous substitution91186
Codons without nonsynonymous substitution13615355
G = 22.95, P < 0.0001a
  • a G = 18.637, P < 0.0001 when codons with more than one synonymous or nonsynonymous substitutions are taken into account.