TABLE 3

Number of tetrads with various segregation patterns for his4 mutant alleles in strains DNY48, PD108, PD99, and DTK158a

StrainAllele4:46:22:65:33:5Ab 4:4Other PMSOther non-PMSTotalAb Seg (%)PMS/Ab Seg. (%)
DNY48bhis4-IR9240151550448613793778
PD108bhis4-712157132701002200222
PD99bhis4-3133218221933396613443767
DTK158his4-IR9184203228433743214359
his4-712224234910120123213024
his4-3133226231616314323213057
  • a For all segregation patterns, the first and second numbers represent the wild-type and mutant alleles, respectively. The classes include the following: 4:4 (normal Mendelian segregation), 6:2 and 2:6 (gene conversion), 5:3 and 3:5 (tetrads with a single PMS event), and Ab 4:4 (aberrant 4:4; one wild-type, one mutant, and two sectored colonies). The “Other PMS” class includes aberrant 6:2, 2:6, 7:1, 1:7 tetrads and tetrads with three or four PMS events; the “Other non-PMS” class consists of 8:0 and 0:8 tetrads.

  • b Detloff and Petes (1992).