Issue Highlights

Perspectives

Genetics Education

Investigations

Genome integrity and transmission

Michelle S. Navarro, Liu Bi, and Adam M. Bailis A Mutant Allele of the Transcription Factor IIH Helicase Gene, RAD3, Promotes Loss of Heterozygosity in Response to a DNA Replication Defect in Saccharomyces cerevisiae Genetics 2007 176: 1391–1402. [Abstract] [Full Text] [PDF]

Anabelle Decottignies Microhomology-Mediated End Joining in Fission Yeast Is Repressed by Pku70 and Relies on Genes Involved in Homologous Recombination Genetics 2007 176: 1403–1415. [Abstract] [Full Text] [PDF] [Data Supplement]

Hong Xu, Charles Boone, and Grant W. Brown Genetic Dissection of Parallel Sister-Chromatid Cohesion Pathways Genetics 2007 176: 1417–1429. [Abstract] [Full Text] [PDF] [Data Supplement]

Ivana Bjedov, Chitralekha Nag Dasgupta, Dea Slade, Sophie Le Blastier, Marjorie Selva, and Ivan Matic Involvement of Escherichia coli DNA Polymerase IV in Tolerance of Cytotoxic Alkylating DNA Lesions in Vivo Genetics 2007 176: 1431–1440. [Abstract] [Full Text] [PDF]

Jeannine R. LaRocque, Diana L. Dougherty, Sumreen K. Hussain, and Jeff Sekelsky Reducing DNA Polymerase in the Absence of Drosophila ATR Leads to P53-Dependent Apoptosis and Developmental Defects Genetics 2007 176: 1441–1451. [Abstract] [Full Text] [PDF]

M. Falque, R. Mercier, C. Mézard, D. de Vienne, and O. C. Martin Patterns of Recombination and MLH1 Foci Density Along Mouse Chromosomes: Modeling Effects of Interference and Obligate Chiasma Genetics 2007 176: 1453–1467. [Abstract] [Full Text] [PDF] [Data Supplement]

Jin Li, Lisa C. Harper, Inna Golubovskaya, C. Rachel Wang, David Weber, Robert B. Meeley, John McElver, Ben Bowen, W. Zacheus Cande, and Patrick S. Schnable Functional Analysis of Maize RAD51 in Meiosis and Double-Strand Break Repair Genetics 2007 176: 1469–1482. [Abstract] [Full Text] [PDF] [Data Supplement]

Qingli L. Liu, Varghese P. Thomas, and Valerie M. Williamson Meiotic Parthenogenesis in a Root-Knot Nematode Results in Rapid Genomic Homozygosity Genetics 2007 176: 1483–1490. [Abstract] [Full Text] [PDF]

Gene expression

X. Bai, E. Larschan, S. Y. Kwon, P. Badenhorst, and M. I. Kuroda Regional Control of Chromatin Organization by Noncoding roX RNAs and the NURF Remodeling Complex in Drosophila melanogaster Genetics 2007 176: 1491–1499. [Abstract] [Full Text] [PDF]

Zhaojun Ding, Mark R. Doyle, Richard M. Amasino, and Seth J. Davis A Complex Genetic Interaction Between Arabidopsis thaliana TOC1 and CCA1/LHY in Driving the Circadian Clock and in Output Regulation Genetics 2007 176: 1501–1510. [Abstract] [Full Text] [PDF] [Data Supplement]

Emma J. Bowles, Joon-Hee Lee, Ramiro Alberio, Rhiannon E. I. Lloyd, Dov Stekel, Keith H. S. Campbell, and Justin C. St. John Contrasting Effects of in Vitro Fertilization and Nuclear Transfer on the Expression of mtDNA Replication Factors Genetics 2007 176: 1511–1526. [Abstract] [Full Text] [PDF]

Cellular genetics

Michael G. Clark and David C. Amberg Biochemical and Genetic Analyses Provide Insight Into the Structural and Mechanistic Properties of Actin Filament Disassembly by the Aip1p–Cofilin Complex in Saccharomyces cerevisiae Genetics 2007 176: 1527–1539. [Abstract] [Full Text] [PDF]

Frederick R. Cross, Lea Schroeder, and James M. Bean Phosphorylation of the Sic1 Inhibitor of B-Type Cyclins in Saccharomyces cerevisiae Is Not Essential but Contributes to Cell Cycle Robustness Genetics 2007 176: 1541–1555. [Abstract] [Full Text] [PDF] [Data Supplement]

Frank Shewmaker, Lori Mull, Toru Nakayashiki, Daniel C. Masison, and Reed B. Wickner Ure2p Function Is Enhanced by Its Prion Domain in Saccharomyces cerevisiae Genetics 2007 176: 1557–1565. [Abstract] [Full Text] [PDF] [Data Supplement]

Developmental and behavioral genetics

Violeta Chávez, Akiko Mohri-Shiomi, Arash Maadani, Luis Alberto Vega, and Danielle A. Garsin Oxidative Stress Enzymes Are Required for DAF-16-Mediated Immunity Due to Generation of Reactive Oxygen Species by Caenorhabditis elegans Genetics 2007 176: 1567–1577. [Abstract] [Full Text] [PDF]

Juliette Mathieu, Hsin-Ho Sung, Céline Pugieux, Jan Soetaert, and Pernille Rorth A Sensitized PiggyBac-Based Screen for Regulators of Border Cell Migration in Drosophila Genetics 2007 176: 1579–1590. [Abstract] [Full Text] [PDF]

Fumi Nakao, Martin L. Hudson, Motoshi Suzuki, Zachary Peckler, Rie Kurokawa, Zhicen Liu, Keiko Gengyo-Ando, Akira Nukazuka, Takashi Fujii, Fumikazu Suto, Yukimasa Shibata, Go Shioi, Hajime Fujisawa, Shohei Mitani, Andrew D. Chisholm, and Shin Takagi The Plexin PLX-2 and the Ephrin EFN-4 Have Distinct Roles in MAB-20/Semaphorin 2A Signaling in Caenorhabditis elegans Morphogenesis Genetics 2007 176: 1591–1607. [Abstract] [Full Text] [PDF]

Aaron N. Johnson, Lindsey A. Burnett, Julia Sellin, Achim Paululat, and Stuart J. Newfeld Defective Decapentaplegic Signaling Results in Heart Overgrowth and Reduced Cardiac Output in Drosophila Genetics 2007 176: 1609–1624. [Abstract] [Full Text] [PDF]

Population and evolutionary genetics

Bastiaan Star, Rick J. Stoffels, and Hamish G. Spencer Single-Locus Polymorphism in a Heterogeneous Two-Deme Model Genetics 2007 176: 1625–1633. [Abstract] [Full Text] [PDF]

Hong Gao, Scott Williamson, and Carlos D. Bustamante A Markov Chain Monte Carlo Approach for Joint Inference of Population Structure and Inbreeding Rates From Multilocus Genotype Data Genetics 2007 176: 1635–1651. [Abstract] [Full Text] [PDF] [Data Supplement]

Dejerianne Ostrow, Naomi Phillips, Arián Avalos, Dustin Blanton, Ashley Boggs, Thomas Keller, Laura Levy, Jeffrey Rosenbloom, and Charles F. Baer Mutational Bias for Body Size in Rhabditid Nematodes Genetics 2007 176: 1653–1661. [Abstract] [Full Text] [PDF] [Data Supplement]

Christoph R. Haag and Denis Roze Genetic Load in Sexual and Asexual Diploids: Segregation, Dominance and Genetic Drift Genetics 2007 176: 1663–1678. [Abstract] [Full Text] [PDF]

Julie A. Kerns, Edward J. Cargill, Leigh Anne Clark, Sophie I. Candille, Tom G. Berryere, Michael Olivier, George Lust, Rory J. Todhunter, Sheila M. Schmutz, Keith E. Murphy, and Gregory S. Barsh Linkage and Segregation Analysis of Black and Brindle Coat Color in Domestic Dogs Genetics 2007 176: 1679–1689. [Abstract] [Full Text] [PDF]

Mikael Brandström and Hans Ellegren The Genomic Landscape of Short Insertion and Deletion Polymorphisms in the Chicken (Gallus gallus) Genome: A High Frequency of Deletions in Tandem Duplicates Genetics 2007 176: 1691–1701. [Abstract] [Full Text] [PDF] [Data Supplement]

J. E. Hubbarde, G. Wild, and L. M. Wahl Fixation Probabilities When Generation Times Are Variable: The Burst–Death Model Genetics 2007 176: 1703–1712. [Abstract] [Full Text] [PDF]

Lilach Hadany and Sarah P. Otto The Evolution of Condition-Dependent Sex in the Face of High Costs Genetics 2007 176: 1713–1727. [Abstract] [Full Text] [PDF]

Meredith V. Trotter and Hamish G. Spencer Frequency-Dependent Selection and the Maintenance of Genetic Variation: Exploring the Parameter Space of the Multiallelic Pairwise Interaction Model Genetics 2007 176: 1729–1740. [Abstract] [Full Text] [PDF]

Michael G. B. Blum and Noah A. Rosenberg Estimating the Number of Ancestral Lineages Using a Maximum-Likelihood Method Based on Rejection Sampling Genetics 2007 176: 1741–1757. [Abstract] [Full Text] [PDF]

Michael M. Desai and Daniel S. Fisher Beneficial Mutation–Selection Balance and the Effect of Linkage on Positive Selection Genetics 2007 176: 1759–1798. [Abstract] [Full Text] [PDF]

David A. Moeller, Maud I. Tenaillon, and Peter Tiffin Population Structure and Its Effects on Patterns of Nucleotide Polymorphism in Teosinte (Zea mays ssp. parviglumis) Genetics 2007 176: 1799–1809. [Abstract] [Full Text] [PDF] [Data Supplement]

Yanchun Li, Yang Li, Song Wu, Kun Han, Zhengjia Wang, Wei Hou, Yanru Zeng, and Rongling Wu Estimation of Multilocus Linkage Disequilibria in Diploid Populations With Dominant Markers Genetics 2007 176: 1811–1821. [Abstract] [Full Text] [PDF]

Genetics of complex traits

Jasmin Divers, Laura K. Vaughan, Miguel A. Padilla, José R. Fernandez, David B. Allison, and David T. Redden Correcting for Measurement Error in Individual Ancestry Estimates in Structured Association Tests Genetics 2007 176: 1823–1833. [Abstract] [Full Text] [PDF]

F. Levillayer, M. Mas, F. Levi-Acobas, M. Brahic, and J. F. Bureau Interleukin 22 Is a Candidate Gene for Tmevp3, a Locus Controlling Theiler's Virus-Induced Neurological Diseases Genetics 2007 176: 1835–1844. [Abstract] [Full Text] [PDF] [Data Supplement]

Malgorzata Zak, Andreas Baierl, Malgorzata Bogdan, and Andreas Futschik Locating Multiple Interacting Quantitative Trait Loci Using Rank-Based Model Selection Genetics 2007 176: 1845–1854. [Abstract] [Full Text] [PDF]

Nengjun Yi, Samprit Banerjee, Daniel Pomp, and Brian S. Yandell Bayesian Mapping of Genomewide Interacting Quantitative Trait Loci for Ordinal Traits Genetics 2007 176: 1855–1864. [Abstract] [Full Text] [PDF]

Nengjun Yi, Daniel Shriner, Samprit Banerjee, Tapan Mehta, Daniel Pomp, and Brian S. Yandell An Efficient Bayesian Model Selection Approach for Interacting Quantitative Trait Loci Models With Many Effects Genetics 2007 176: 1865–1877. [Abstract] [Full Text] [PDF]

Wei Zhao, Hongying Li, Wei Hou, and Rongling Wu Wavelet-Based Parametric Functional Mapping of Developmental Trajectories With High-Dimensional Data Genetics 2007 176: 1879–1892. [Abstract] [Full Text] [PDF]

W. Barendse, A. Reverter, R. J. Bunch, B. E. Harrison, W. Barris, and M. B. Thomas A Validated Whole-Genome Association Study of Efficient Food Conversion in Cattle Genetics 2007 176: 1893–1905. [Abstract] [Full Text] [PDF] [Data Supplement]

Genome and systems biology

David L'Hôte, Catherine Serres, Paul Laissue, Ahmad Oulmouden, Claire Rogel-Gaillard, Xavier Montagutelli, and Daniel Vaiman Centimorgan-Range One-Step Mapping of Fertility Traits Using Interspecific Recombinant Congenic Mice Genetics 2007 176: 1907–1921. [Abstract] [Full Text] [PDF]

Notes

Population and evolutionary genetics

Floyd A. Reed Two-Locus Epistasis With Sexually Antagonistic Selection: A Genetic Parrondo's Paradox Genetics 2007 176: 1923–1929. [Abstract] [Full Text] [PDF] [Data Supplement]

J. C. Reif, F.-M. Gumpert, S. Fischer, and A. E. Melchinger Impact of Interpopulation Divergence on Additive and Dominance Variance in Hybrid Populations Genetics 2007 176: 1931–1934. [Abstract] [Full Text] [PDF]

Lars Rönnegård, Kateryna Mischenko, Sverker Holmgren, and Örjan Carlborg Increasing the Efficiency of Variance Component Quantitative Trait Loci Analysis by Using Reduced-Rank Identity-by-Descent Matrices Genetics 2007 176: 1935–1938. [Abstract] [Full Text] [PDF]

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