About the Cover

About the Cover
A rosette of maturing asci of Neurospora crassa, from wild type × histone H1-GFP (inserted at his-3). Histone H1, being a chromosomal protein, allows the GFP-tagged nuclei (two per spore at this stage) to fluoresce in four of the eight ascospores of each ascus; the remaining four ascospores carry the untagged nuclei from the wild-type parent. In heterozygous asci, hH1-GFP is silenced during meiosis but is re-expressed in the autonomously developing ascospores. Almost all asci show the first-division segregation of hH1-GFP because of its close proximity to the centromere of linkage group I. See RAJU et al. (pp. 43–52) for details.