July 2016 Table of Contents

Investigations

• Statistical Genetics and Genomics

  • Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies

    Brielin C. Brown, Alkes L. Price, Nikolaos A. Patsopoulos, Noah Zaitlen

    Genetics July 2016 203: 1105-1116; https://doi.org/10.1534/genetics.116.188292

• Genome Integrity and Transmission

  • A Parthenogenesis Gene Candidate and Evidence for Segmental Allopolyploidy in Apomictic Brachiaria decumbens

    Open Access

    Margaret Worthington, Christopher Heffelfinger, Diana Bernal, Constanza Quintero, Yeny Patricia Zapata, Juan Guillermo Perez, Jose De Vega, John Miles, Stephen Dellaporta, Joe Tohme

    Genetics July 2016 203: 1117-1132; https://doi.org/10.1534/genetics.116.190314

• Gene Expression

  • Genes and Small RNA Transcripts Exhibit Dosage-Dependent Expression Pattern in Maize Copy-Number Alterations

    Tao Zuo, Jianbo Zhang, Andrew Lithio, Sudhansu Dash, David F. Weber, Roger Wise, Dan Nettleton, Thomas Peterson

    Genetics July 2016 203: 1133-1147; https://doi.org/10.1534/genetics.116.188235
  • A Novel Strategy for Exploitation of Host RNase E Activity by a Marine Cyanophage

    Damir Stazic, Irena Pekarski, Matthias Kopf, Debbie Lindell, Claudia Steglich

    Genetics July 2016 203: 1149-1159; https://doi.org/10.1534/genetics.115.183475
  • Phenotypic Consequences of a Spontaneous Loss of Heterozygosity in a Common Laboratory Strain of Candida albicans

    Toni Ciudad, Meleah Hickman, Alberto Bellido, Judith Berman, Germán Larriba

    Genetics July 2016 203: 1161-1176; https://doi.org/10.1534/genetics.116.189274
  • Buffering of Genetic Regulatory Networks in Drosophila melanogaster

    Justin M. Fear, Luis G. León-Novelo, Alison M. Morse, Alison R. Gerken, Kjong Van Lehmann, John Tower, Sergey V. Nuzhdin, Lauren M. McIntyre

    Genetics July 2016 203: 1177-1190; https://doi.org/10.1534/genetics.116.188797

• Cellular Genetics

  • The Activity-Dependent Regulation of Protein Kinase Stability by the Localization to P-Bodies

    Bo Zhang, Qian Shi, Sapna N. Varia, Siyuan Xing, Bethany M. Klett, Laura A. Cook, Paul K. Herman

    Genetics July 2016 203: 1191-1202; https://doi.org/10.1534/genetics.116.187419
  • Timely Closure of the Prospore Membrane Requires SPS1 and SPO77 in Saccharomyces cerevisiae

    Scott M. Paulissen, Christian J. Slubowski, Joseph M. Roesner, Linda S. Huang

    Genetics July 2016 203: 1203-1216; https://doi.org/10.1534/genetics.115.183939
  • Complex Haploinsufficiency-Based Genetic Analysis of the NDR/Lats Kinase Cbk1 Provides Insight into Its Multiple Functions in Candida albicans

    Sarah Saputo, Kaitlyn L. Norman, Thomas Murante, Brooke N. Horton, Jacinto De La Cruz Diaz, Louis DiDone, Jennifer Colquhoun, Jeremy W. Schroeder, Lyle A. Simmons, Anuj Kumar, Damian J. Krysan

    Genetics July 2016 203: 1217-1233; https://doi.org/10.1534/genetics.116.188029

• Developmental and Behavioral Genetics

  • Pioneer Axon Navigation Is Controlled by AEX-3, a Guanine Nucleotide Exchange Factor for RAB-3 in Caenorhabditis elegans

    Jaffar M. Bhat, Harald Hutter

    Genetics July 2016 203: 1235-1247; https://doi.org/10.1534/genetics.115.186064
  • Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9

    Silvia Schwartz, Mauro Truglio, Maxwell J. Scott, Helen L. Fitzsimons

    Genetics July 2016 203: 1249-1264; https://doi.org/10.1534/genetics.115.183194
  • Roles for the Histone Modifying and Exchange Complex NuA4 in Cell Cycle Progression in Drosophila melanogaster

    Kerry Flegel, Olga Grushko, Kelsey Bolin, Ellen Griggs, Laura Buttitta

    Genetics July 2016 203: 1265-1281; https://doi.org/10.1534/genetics.116.188581
  • Retinal Axon Guidance Requires Integration of Eya and the Jak/Stat Pathway into Phosphotyrosine-Based Signaling Circuitries in Drosophila

    Charlene S. L. Hoi, Wenjun Xiong, Ilaria Rebay

    Genetics July 2016 203: 1283-1295; https://doi.org/10.1534/genetics.115.185918

• Population and Evolutionary Genetics

  • How Life History Can Sway the Fixation Probability of Mutants

    Xiang-Yi Li, Shun Kurokawa, Stefano Giaimo, Arne Traulsen

    Genetics July 2016 203: 1297-1313; https://doi.org/10.1534/genetics.116.188409
  • Resolving the Conflict Between Associative Overdominance and Background Selection

    Lei Zhao, Brian Charlesworth

    Genetics July 2016 203: 1315-1334; https://doi.org/10.1534/genetics.116.188912
  • Epistasis and the Dynamics of Reversion in Molecular Evolution

    David M. McCandlish, Premal Shah, Joshua B. Plotkin

    Genetics July 2016 203: 1335-1351; https://doi.org/10.1534/genetics.116.188961
  • Genomic Conflicts that Cause Pollen Mortality and Raise Reproductive Barriers in Arabidopsis thaliana

    Matthieu Simon, Stéphanie Durand, Natacha Pluta, Nicolas Gobron, Lucy Botran, Anthony Ricou, Christine Camilleri, Françoise Budar

    Genetics July 2016 203: 1353-1367; https://doi.org/10.1534/genetics.115.183707
  • Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria

    Alejandro Couce, Alexandro Rodríguez-Rojas, Jesús Blázquez

    Genetics July 2016 203: 1369-1380; https://doi.org/10.1534/genetics.115.185355
  • Two-Locus Likelihoods Under Variable Population Size and Fine-Scale Recombination Rate Estimation

    John A. Kamm, Jeffrey P. Spence, Jeffrey Chan, Yun S. Song

    Genetics July 2016 203: 1381-1399; https://doi.org/10.1534/genetics.115.184820
  • Heterozygote Advantage Is a Common Outcome of Adaptation in Saccharomyces cerevisiae

    Diamantis Sellis, Daniel J. Kvitek, Barbara Dunn, Gavin Sherlock, Dmitri A. Petrov

    Genetics July 2016 203: 1401-1413; https://doi.org/10.1534/genetics.115.185165

• Genetics of Complex Traits

  • Extra Microchromosomes Play Male Determination Role in Polyploid Gibel Carp

    Xi-Yin Li, Qi-Ya Zhang, Jun Zhang, Li Zhou, Zhi Li, Xiao-Juan Zhang, Da Wang, Jian-Fang Gui

    Genetics July 2016 203: 1415-1424; https://doi.org/10.1534/genetics.115.185843
  • Increased Proportion of Variance Explained and Prediction Accuracy of Survival of Breast Cancer Patients with Use of Whole-Genome Multiomic Profiles

    Open Access

    Ana I. Vazquez, Yogasudha Veturi, Michael Behring, Sadeep Shrestha, Matias Kirst, Marcio F. R. Resende, Gustavo de los Campos

    Genetics July 2016 203: 1425-1438; https://doi.org/10.1534/genetics.115.185181
  • Hybrid Sterility in Rice (Oryza sativa L.) Involves the Tetratricopeptide Repeat Domain Containing Protein

    Yang Yu, Zhigang Zhao, Yanrong Shi, Hua Tian, Linglong Liu, Xiaofeng Bian, Yang Xu, Xiaoming Zheng, Lu Gan, Yumin Shen, Chaolong Wang, Xiaowen Yu, Chunming Wang, Xin Zhang, Xiuping Guo, Jiulin Wang, Hiroshi Ikehashi, Ling Jiang, Jianmin Wan

    Genetics July 2016 203: 1439-1451; https://doi.org/10.1534/genetics.115.183848
  • Development and Genetic Characterization of an Advanced Backcross-Nested Association Mapping (AB-NAM) Population of Wild × Cultivated Barley

    Liana M. Nice, Brian J. Steffenson, Gina L. Brown-Guedira, Eduard D. Akhunov, Chaochih Liu, Thomas J. Y. Kono, Peter L. Morrell, Thomas K. Blake, Richard D. Horsley, Kevin P. Smith, Gary J. Muehlbauer

    Genetics July 2016 203: 1453-1467; https://doi.org/10.1534/genetics.116.190736

• Genome and System Biology

  • Novel Intronic RNA Structures Contribute to Maintenance of Phenotype in Saccharomyces cerevisiae

    Open Access

    Katarzyna B. Hooks, Samina Naseeb, Steven Parker, Sam Griffiths-Jones, Daniela Delneri

    Genetics July 2016 203: 1469-1481; https://doi.org/10.1534/genetics.115.185363