A Novel Cell Death Gene Acts to Repair Patterning Defects in Drosophila melanogaster
Kentaro M. Tanaka, Aya Takahashi, Naoyuki Fuse, Toshiyuki Takano-Shimizu-Kouno

Abstract

Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.

  • Received February 21, 2014.
  • Accepted March 24, 2014.
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