A Novel Cell Death Gene Acts to Repair Patterning Defects in Drosophila melanogaster
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.
- Received February 21, 2014.
- Accepted March 24, 2014.
- Copyright © 2014 by the Genetics Society of America