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doi:10.1534/genetics.106.066472
A more recent version of this article appeared on June 1, 2007.
GENETICS EDUCATION |
Involving Undergraduates in the Annotation and Analysis of Global Gene Expression Studies: Creation of a Maize Shoot Apical Meristem Expression Database
Brent Buckner 1, Jon Beck 1, Kate F. Browning 1, Ashleigh E. Fritz 1, Eneda Hoxha 1, Lisa D. Grantham 1, Zhian N. Kamvar 1, Ashley N. Lough 1, Olga Nikolova 1, Patrick S. Schnable 2, Michael J. Scanlon 3 and Diane Janick-Buckner 1*
1 Truman State University
2 Iowa State University
3 Cornell University
* To whom correspondence should be addressed. E-mail: djb{at}truman.edu.
Submitted on October 4, 2006
Revised on November 10, 2006
Accepted on 13 March 2007
Through a multi-university and interdisciplinary project we have involved undergraduate biology and computer science research students in the functional annotation of maize genes and analysis of their microarray expression patterns. We have created a database to house the results of our functional annotation of over 4,400 genes that were identified as being differentially regulated in the maize shoot apical meristem (SAM). This database is located at http://sam.truman.edu and is now available for public use. The undergraduate students involved in constructing this unique SAM database received hands-on training in an intellectually challenging environment, which has prepared them for graduate and professional careers in biological sciences. We describe our experiences with this project as a model for effective research-based teaching of undergraduate biology and computer science students, as well as a rich professional development experience for faculty at predominantly undergraduate institutions.
Key Words: bioinformatics education, functional annotation, maize, shoot apical meristem, undergraduate research
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