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doi:10.1534/genetics.106.057414
A more recent version of this article appeared on September 1, 2006.
REGULAR RESEARCH PAPERS |
No accelerated rate of protein evolution in male biased Drosophila pseudoobscura genes
Muralidhar Metta 1, Rambabu Gudavalli 1, Jean-Michel Gibert 1 and Christian Schlotterer 2*
1 VMU Wien
2 Institut fuer Tierzucht und Genetik
* To whom correspondence should be addressed. E-mail: christian.schloetterer{at}vu-wien.ac.at.
Submitted on February 19, 2006
Revised on March 24, 2006
Accepted on 20 June 2006
Sexually dimorphic traits are subject to diversifying selection. Also genes with a male biased gene expression are probably affected by sexual selection and have a high rate of protein evolution. We used SAGE to measure sex biased gene expression in Drosophila pseudoobscura. Consistent with previous results from D. melanogaster, a larger number of genes were male biased (402 genes) than female biased (138 genes). About 34% of the genes changed the sex related expression pattern between D. melanogaster and D. pseudoobscura. Combining gene expression with protein divergence between both species, we observed a striking difference in rate of evolution for genes with a male biased gene expression in one species only. Contrary to expectations, D. pseudoobscura genes in this category showed no accelerated rate of protein evolution, while D. melanogaster genes did. If sexual selection is driving molecular evolution of male biased genes, our data imply a radically different selection regime in D. pseudoobscura. Alternatively, the data may also be explained by relaxed selective constraint.
Key Words: SAGE, gene expression, male bias, rate of evolution, selection
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