- THIS ARTICLE
- Full Text (Rapid PDF)
-
All Versions of this Article:
genetics.106.057273v1
174/2/795 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Frisch, M.
- Articles by Melchinger, A. E.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Frisch, M.
- Articles by Melchinger, A. E.
doi:10.1534/genetics.106.057273
A more recent version of this article appeared on October 1, 2006.
REGULAR RESEARCH PAPERS |
Marker-based prediction of the parental genome contribution to inbred lines derived from biparental crosses
Matthias Frisch 1 and Albrecht E. Melchinger 1*
1 University of Hohenheim
* To whom correspondence should be addressed. E-mail: melchinger{at}uni-hohenheim.de.
Submitted on February 17, 2006
Revised on April 18, 2006
Accepted on 25 July 2006
Molecular markers can be employed to predict the parental genome contribution to inbred lines. The proportion 
of alleles originating from parent P1 at markers polymorphic between the parental lines P1 and P2 is commonly used as a predictor for the genome contribution of parent P1 to an offspring line. Our objectives were to develop a new marker-based predictor 
for the parental genome contribution, which takes not only the alleles at marker loci but also their map distance into account, and to compare the prediction precision of with that of alternative methods. We derived formulas for for inbreds derived from biparental crosses (F1 and backcrosses) with the single-seed descent or double haploid method and presented an extension * possessing statistical optimum properties. In a simulation study, showed a systematic overestimation of large parental genome contribution that was not observed for . The mean squared prediction error of was at least 50% smaller than that of for linkage maps with unequal distances between adjacent markers. A data set from a study on plant variety protection in maize was used to illustrate the application of . We conclude that provides substantially greater prediction precision than the commonly used predictor in a broad range of applications in genetics and breeding.
Key Words: Optimum prediction, donor genome, genome proportion, inbred lines
This article has been cited by other articles:
 |
|
 |
|
  S. Smith Intellectual Property Protection for Plant Varieties in the 21st Century Crop Sci., July 1, 2008; 48(4): 1277 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. E. Melchinger, H. F. Utz, H.-P. Piepho, Z.-B. Zeng, and C. C. Schon The Role of Epistasis in the Manifestation of Heterosis: A Systems-Oriented Approach Genetics, November 1, 2007; 177(3): 1815 - 1825. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Frisch and A. E. Melchinger Variance of the Parental Genome Contribution to Inbred Lines Derived From Biparental Crosses Genetics, May 1, 2007; 176(1): 477 - 488. [Abstract] [Full Text] [PDF]
|
|
|