- THIS ARTICLE
- Full Text (Rapid PDF)
-
All Versions of this Article:
genetics.105.052993v1
173/1/215 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Moehring, A. J.
- Articles by Mackay, T. F.C.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Moehring, A. J.
- Articles by Mackay, T. F.C.
doi:10.1534/genetics.105.052993
A more recent version of this article appeared on May 1, 2006.
REGULAR RESEARCH PAPERS |
The Genetic Basis of Prezygotic Reproductive Isolation Between Drosophila santomea and D. yakuba Due to Mating Preference
Amanda J. Moehring 1*, Ana Llopart 2, Susannah Elwyn 3, Jerry A Coyne 4 and Trudy F.C. Mackay 5
1 Duke University
2 University of Iowa
3 Harvard Medical School
4 University of Chicago
5 North Carolina State University
* To whom correspondence should be addressed. E-mail: ajmoehring{at}gmail.com.
Submitted on October 31, 2005
Revised on January 20, 2006
Accepted on 17 February 2006
Sexual isolating mechanisms that act before fertilization are often considered the most important genetic barriers leading to speciation in animals. While progress has been made towards understanding the genetic basis of the postzygotic isolating mechanisms of hybrid sterility and inviability, little is known about the genetic basis of prezygotic sexual isolation. Here, we map quantitative trait loci (QTLs) contributing to prezygotic reproductive isolation between the sibling species Drosophila santomea and D. yakuba. We mapped at least three QTLs affecting discrimination of D. santomea females against D. yakuba males: one X-linked and one autosomal QTL affected the likelihood of copulation, and a second X chromosome QTL affected copulation latency. Three autosomal QTLs also affected mating success of D. yakuba males with D. santomea. No epistasis was detected between QTLs affecting sexual isolation. The QTLs do not overlap between males and females, and are not disproportionately concentrated on the X chromosome. There was some overlap in map locations of QTLs affecting sexual isolation between D. santomea and D. yakuba with QTLs affecting sexual isolation between D. simulans and D. mauritiana, and with QTLs affecting differences in pigmentation between D. santomea and D. yakuba. Future high-resolution mapping and, ultimately, positional cloning, will reveal whether these traits do indeed have a common genetic basis.
Key Words: QTL mapping, courtship behavior, reproductive isolation, speciation
This article has been cited by other articles:
 |
|
 |
|
  N. H. Martin, A. C. Bouck, and M. L. Arnold The Genetic Architecture of Reproductive Isolation in Louisiana Irises: Flowering Phenology Genetics, April 1, 2007; 175(4): 1803 - 1812. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. C. Moyle Comparative Genetics of Potential Prezygotic and Postzygotic Isolating Barriers in a Lycopersicon Species Cross J. Hered., March 1, 2007; 98(2): 123 - 135. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Moehring, A. Llopart, S. Elwyn, J. A. Coyne, and T. F. C. Mackay The Genetic Basis of Postzygotic Reproductive Isolation Between Drosophila santomea and D. yakuba Due to Hybrid Male Sterility Genetics, May 1, 2006; 173(1): 225 - 233. [Abstract] [Full Text] [PDF]
|
|