Genetics. Published Articles Ahead of Print: November 15, 2004, Copyright © 2004
doi:10.1534/genetics.104.027748


A more recent version of this article appeared on March 1, 2005.

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Many P-element insertions affect wing shape in Drosophila melanogaster

Kenneth Weber 1*, Nancy Johnson 1, David Champlin 1 and April Patty 1

1 University of Southern Maine

* To whom correspondence should be addressed. E-mail: keweber{at}usm.maine.edu.

Submitted on February 18, 2004
Revised on April 26, 2004
Accepted on 8 November 2004


Abstract

A screen of random, autosomal, homozygous-viable P-element insertions in D. melanogaster found small effects on wing shape in 11 of 50 lines. The effects were due to single insertions and remained stable and significant for over five years in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.

Key Words: development, drosophila, morphology, quantitative trait genes, wings




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