Genetics, Vol. 171, 1441-1442, November 2005, Copyright © 2005
doi:10.1534/genetics.104.029769

Effective Population Size Under Random Mating With a Finite Number of Matings

Tetsuro Nomura1

Department of Biotechnology, Faculty of Engineering, Kyoto Sangyo University, Kyoto 603-8555, Japan

1 Author e-mail: nomurat{at}cc.kyoto-su.ac.jp

Manuscript received April 7, 2004. Accepted for publication June 7, 2005.

RANDOM union of gametes (RUG) is the null model central to theoretical population genetics. In this model, all male and female parents contribute their gametes equally to male and female gametic pools, respectively. Zygotes (offspring) are produced by random union of gametes, each from the male and female gametic pools. One assumption behind this model is that individuals mate an infinite number of times. Some organisms reproduce more or less in a fashion like the RUG model. For example, some aquatic animals release large numbers of gametes into the ocean, and some wind-pollinated plants release vast numbers of male gametes (FALCONER 1989). However, this mating system is in reality rather rare. In most animal mating systems, individuals (rather than gametes) come together to mate. Even in some plant systems, this is effectively the case whenever a mass of pollen from a single donor plant is transferred to another plant (NUNNEY 1993).

Recently, BALLOUX and LEHMANN (2003) relaxed the assumption of the RUG model, by allowing females to mate an arbitrary number of times. From a consideration of coalescence times, they derived an equation of the effective population size () with an arbitrary number of matings. In a similar context, NOMURA (2002a) independently developed an equation of the effective population size. As shown in the following, the equation of BALLOUX and LEHMANN (2003) is a special form of the more general result given by NOMURA (2002a).

Consider a population of dioecious species, in which males mate randomly with females. Subscript s (denoting m or f) is used to specify sex. Let be the number of matings of parent of sex s, with the mean and variance . There are matings in the population. Then, and . Assuming a Poisson distribution of litter size (the number of newborns per mating), the equation given by NOMURA (2002a) reduces to

(1)
where is the coefficient of variation of .

In the model of BALLOUX and LEHMANN (2003), females are assumed to mate with a fixed number of randomly sampled males. Thus, and . For males, the number of matings () will follow a binomial distribution with the mean and variance , giving

Substituting these expressions into Equation 1 leads to

This agrees with Equation 7 in BALLOUX and LEHMANN (2003), but with the neglect of two minor terms in their equation. It is more realistic to allow a variation in the number of matings for females (). If follows a Poisson distribution, . Thus, the effective population size is expressed as

More generally, assuming that the number of matings follows a Poisson distribution within each sex, Equation 1 is written as

One of the most interesting applications of Equation 1 is that to harem polygamy in animals. In traditional works (e.g., CHEPKO-SADE et al. 1987), the effective population size under harem polygamy has been estimated with a well-known formula of WRIGHT (1931):

(2)
However, this formula is based on the RUG model and holds under random mating with a finite number of matings only when there are no variations in the mating numbers within each sex; i.e., . A more appropriate equation, but with a simplicity comparable to Equation 2, is obtained from Equation 1. Under harem polygamy, successful males generally mate with most or all of the females in their harem, and the females generally mate with only one male. Thus, , and if the number of matings per male (harem size) follows a Poisson distribution. Then, from Equation 1, the effective population size is estimated by

Other applications including the extension to sex-linked locus or haplo-diploid species are shown in NOMURA (2002a).

Finally, the difference between the RUG model and random mating with a finite number of matings is specially important for considering the effect of heritable variation in fitness on the effective population size. The expected fitness of a parent under the RUG model is not affected by the genotypes of mates, because they are randomly sampled from the population. Thus, fitness in this model should be defined for individual parents. In contrast, under random mating with a finite number of matings, fitness should be defined for couples in monogamy and families in polygamy or polyandry. Further discussion on this topic and on the formulation of effective population size can be seen in NOMURA (2002b).

ACKNOWLEDGEMENTS

This work was supported in part by grants-in-aid for scientific research (nos. 14560241 and 15658076) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

LITERATURE CITED

BALLOUX, F., and L. LEHMANN, 2003 Random mating with a finite number of matings. Genetics 165: 2313–2315.[Abstract/Free Full Text]

CHEPKO-SADE, B. D., W. M. SHIELDS, J. BERGER, Z. T. HALPIN, W. T. JONES et al., 1987 The effects of dispersal and social structure on effective population size, pp. 287–321 in Mammalian Dispersal Patterns: The Effects of Social Structure on Population Genetics, edited by B. D. CHEPKO-SADE and Z. T. HALPIN. University of Chicago Press, Chicago.

FALCONER, D. S., 1989 Introduction to Quantitative Genetics, Ed. 3. Longman Harlow, Essex, UK.

NOMURA, T., 2002a Effective size of populations with unequal sex ratio and variation in mating success. J. Anim. Breed. Genet. 118: 297–310.

NOMURA, T., 2002b Effective size of populations with heritable variation in fitness. Heredity 89: 413–416.[Medline]

NUNNEY, L., 1993 The influence of mating system and overlapping generations on effective population size. Evolution 47: 1329–1341.[CrossRef]

WRIGHT, S., 1931 Evolution in Mendelian populations. Genetics 16: 97–159.[Free Full Text]

Communicating editor: M. UYENOYAMA