Originally published as Genetics Published Articles Ahead of Print on November 15, 2004.

Genetics, Vol. 169, 1461-1475, March 2005, Copyright © 2005
doi:10.1534/genetics.104.027748

Many P-Element Insertions Affect Wing Shape in Drosophila melanogaster

Department of Biological Sciences, University of Southern Maine, Portland, Maine 04104-9300

1 Corresponding author: Department of Biological Sciences, University of Southern Maine, Box 9300, Portland, ME 04104-9300.
E-mail: keweber{at}usm.maine.edu

A screen of random, autosomal, homozygous-viable P-element insertions in D. melanogaster found small effects on wing shape in 11 of 50 lines. The effects were due to single insertions and remained stable and significant for over 5 years, in repeated, high-resolution measurements. All 11 insertions were within or near protein-coding transcription units, none of which were previously known to affect wing shape. Many sites in the genome can affect wing shape.




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