Supplement to Ames et al., 2008

Supplemental Files

Files in this Data Supplement:

• Supplemental Figure 1 - "Supplemental Figure. 1. Distribution of mlTRs and slTRs across individual human autosomes. Tandem repeats on each of the human chromosomes are shown distributed across their physical lengths, which have been normalized to “1” along the x-axis. The two parallel dotted lines indicate the approximate centromeric region of the chromosome. The numbers of both slTRs and mlTRs in 0.5% intervals across the chromosome were summed and plotted on the y-axis."
• Supplemental Data 1 - "Supplemental Data 1. Compilation of IDs from TRDB defining the slTRs and mlTRs."
• Supplemental Data 4 - "Supplemental Data 4. BED files of three epigenetically-regulated gene classes we investigated in this study (i.e. imprinted, tandem repeat disease, and tumor suppressor). These files may be used as custom tracks in the UCSC Genome Browser. (The fourth class of gene (i.e. all) is the Ensembl genebuild, which is available as a standard track.)"
• Supplemental Table 1 - "Supplemental Table 1. Listing of genes included in subclasses. First worksheet lists 45 genes used in the analyses and annotated as imprinted. The second worksheet lists 182 genes that were analyzed as comprising a tumor suppressor gene subclass. The third worksheet summarizes the 24 genes that have been implicated in human disease due to tandem repeat expansion."
• Supplemental Data 3 - "Supplemental Data 3. BED files of tandem repeats presumed to represent highly polymorphic molecular markers. slTRs were screened for those with five or more repeats and match percentage of 95% or greater. This file is intended for use as a custom track in the UCSC Genome Browser."
• Supplemental Data 2 - "Supplementary File 2. BED files for each of the four tandem repeat classes (i.e. mlTRs, slTRs, repTRs, notRepTRs). These files are intended for use as custom tracks in the UCSC Genome Browser."