Supplement to Mutiu et al., 2007

Supplemental Figure and Tables

Files in this Data Supplement:

• Supplemental Table 2 - "Supplemental Table 2"
• Supplemental Figure 1 - "ClustalW alignment of the PI3K domain of Tra1 related molecules. Sequences are from S. cerevisiae (Tra1, NP011967), S. paradoxus (Spar, MIT-Spar_c34_10007), S. castellii (Scas, WashU_Scas_Contig658.18), N. crassa (Ncra, CAC18279), S. pombe (Spom, NP595777), S. pombe (Spo2, Q10064), Homo sapiens (Hsap, NP003487). The consensus sequence is shown below these sequences with the mutagenized residues color-coded (red, inviable; green, viable; blue, very slow growing; magenta, temperature sensitive). Comparable positions of porcine PI3K-gamma (PI3K; Walker et al., 1999) and DNA dependent protein kinase (DnaPK; P78527) are shown aligned (SMART) with structural features of porcine PI3K-gamma (NP_999104 Walker et al., 1999). Numbering for PI3K-gamma and DNA-PK are for the first amino acids indicated in each row. N3580 is the position of the BamHI site in the TRA1SB allele."
• Supplemental Table 1 - "Supplemental Table 1"