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FATE MAPPING MULTI-FOCUS PHENOTYPES
Jonathan Arnold 1 and Douglas R. Kankel 2
1 Department of Statistics, Yale University, 2179 Yale Station, New Haven, CT 06520
2 Department of Biology, Yale University, Box 6666, 260 Whitney Ave., New Haven, CT 06511
A central assumption used in the genetic fate mapping of anatomical sites responsible for certain mutationally induced abnormalities is that a single pair of bilaterally symmetric sites on the blastoderm gives rise to structures that control the expression of that abnormality. We report a new model that is not so constrained and test its efficacy in the analysis of several mutations that induce behavioral abnormalities.
Submitted on June 3, 1981Revised on August 10, 1981