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THE DETECTION OF MUTANTS IN MICE BY ELECTROPHORESIS: RESULTS OF A MODEL INDUCTION EXPERIMENT WITH PROCARBAZINE
F. M. Johnson , G. T. Roberts , R. K. Sharma , Fred Chasalow , Ruth Zweidinger , Ann Morgan , R. Wayne Hendren , and Susan E. Lewis
Male mice of the DBA/2J strain were treated with the mutagen procarbazine and mated with C57BL/6J females. Offspring and parents were then analyzed for electrophoretically expressed mutations. A control group, not mutagen treated, was also examined. Two mutants probably due to induction were identified, and several of spontaneous origin were also found.
Submitted on May 15, 1980Revised on December 8, 1980
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