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ESTIMATION OF AVERAGE HETEROZYGOSITY AND GENETIC DISTANCE FROM A SMALL NUMBER OF INDIVIDUALS
Masatoshi Nei 1
1 Center for Demographic and Population Genetics, University
of Texas at Houston, Texas 77025
The magnitudes of the systematic biases involved in sample heterozygosity and sample genetic distances are evaluated, and formulae for obtaining unbiased estimates of average heterozygosity and genetic distance are developed. It is also shown that the number of individuals to be used for estimating average heterozygosity can be very small if a large number of loci are studied and the average heterozygosity is low. The number of individuals to be used for estimating genetic distance can also be very small if the genetic distance is large and the average heterozygosity of the two species compared is low.
Submitted on November 1, 1977Revised on February 13, 1978
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Y. Liu, Y. Wang, and H. Huang High interpopulation genetic differentiation and unidirectional linear migration patterns in Myricaria laxiflora (Tamaricaceae), an endemic riparian plant in the Three Gorges Valley of the Yangtze River Am. J. Botany, February 1, 2006; 93(2): 206 - 215. [Abstract] [Full Text] [PDF] |
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