DISTRIBUTION AND FREQUENCY OF TANDEM DUPLICATIONS OF THE rII REGION OF BACTERIOPHAGE T4D

David H. Parma 1, G. Thomas Heath 1, Chia-Chung Che 1, and J. L. Annest 1

1 Department of Biology, University of Utah, Salt Lake City, Utah 84112

Genetic analyses of 49 duplications of the rII region of bacteriophage T4D suggests that there is a non-random relationship between the end points of duplicated segments, that relaxed packaging restrictions have little if any effect on the distribution of duplications, that segregation is 3–4 times more frequent than normal recombination for the same interval, and that non-tandem duplications are rare. Extrapolation of the r1231 x rJ101 cross data suggests that the minimum frequency of duplications/genome is 1.7 x 10-6, but possibly 3.4 x 10-4.

Submitted on December 29, 1975
Revised on June 27, 1977