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GENETICS OF CYCLOHEXIMIDE RESISTANCE IN TETRAHYMENA
Lea K. Bleyman 1 and Peter J. Bruns 2
1 Department of Natural Sciences, Baruch College, C.U.N.Y., New York, New York 10010
2 Section of Genetics, Development and Physiology, Cornell University, Ithaca, New York 14853
Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro- and macro-nuclei of this organism for genetic studies.
Submitted on February 2, 1977Revised on July 14, 1977
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E Orias, E. Hamilton, and M Flacks Osmotic shock prevents nuclear exchange and produces whole-genome homozygotes in conjugating Tetrahymena Science, February 16, 1979; 203(4381): 660 - 663. [Abstract] [PDF]
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