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LACK OF DOSAGE COMPENSATION FOR AN AUTOSOMAL GENE RELOCATED TO THE X CHROMOSOME IN DROSOPHILA MELANOGASTER
Richard L. Roehrdanz 1, James M. Kitchens 1, and John C. Lucchesi 1
1 Department of Zoology and Genetics Curriculum, University
of North Carolina, Chapel Hill, North Carolina 27514
Aldehyde oxidase activity has been measured in flies with the structural gene for this enzyme translocated to the X chromosome. These measurements are presented as experimental evidence that, in Drosophila melanogaster, an autosomal gene relocated to the X chromosome is not dosage compensated.
Submitted on September 16, 1976Revised on November 29, 1976
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  J. Lucchesi Gene dosage compensation and the evolution of sex chromosomes Science, November 17, 1978; 202(4369): 711 - 716. [Abstract] [PDF]
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