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GENE CONVERSION: A HITHERTO OVERLOOKED PARAMETER IN POPULATION GENETICS
Herbert Gutz 1 and John F. Leslie 1
1 Institute for Molecular Biology, The University of Texas at
Dallas, Richardson, Texas 75080
Gene conversion causes deviations from the 2:2 segregation of allele pairs in meiosis. Thus, gene conversion is a potential cause for changes of allele frequencies in populations. Equations are derived for the effects of conversion in a large random-mating population. The influence of gene conversion on allele frequencies is compared with that of spontaneous mutation and meiotic drive.
Submitted on July 28, 1975Revised on December 1, 1975
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