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- Articles by Manney, T. R.
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MUTANTS OF SACCHAROMYCES CEREVISIAE RESISTANT TO THE 
MATING-TYPE FACTOR
Thomas R. Manney 1 and Verna Woods 1
1 Department of Physics, Kansas State University, Manhattan,
Kansas 66506
Mutants that are resistant to 
-factor have been isolated
from a mating-type haploid strains of yeast by direct selection on
agar medium containing partially purified -factor. All resistant mutants
isolated were found to be sterile. They were characterized and compared with
mutants previously isolated as nonmating. Among 93 able to mate at low frequency
and to sporulate, none showed linkage to the mating-type locus. The results
support the hypothesis that the response to -factor by cells of mating-type
a is essential for mating.
Revised on November 20, 1975