MUTATIONS MASKING THE LAMBDA CIN-1 MUTATION

Matthew McDermit ¹, Mark Pierce ¹, Darrell Staley ¹, Michael Shimaji ¹, Richard Shaw ¹, and Daniel L. Wulff ¹

¹ Department of Molecular Biology and Biochemistry, University of California at Irvine, Irvine, California 92717

A lambda cnc mutation masks the phenotype of the lambda cin-1 mutation. Eleven cnc mutations have been found. All appear to be identical and all map at a site just to the right of the cin-1 site. It is probable that cin-1 and cnc affect adjacent, or almost adjacent nucleotide pairs. Neither the cin-1 nor the cnc mutation involves large additions or deletions of genetic material.