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ON INVERTED REPEAT SEQUENCES IN CHROMOSOMAL DNA
Bruce Wallace 1 and Thomas L. Kass 1
1 Cornell University, Ithaca, N. Y. 14853
It is suggested that chromosomal DNA should contain a class of palindromic reverse repeats, comparable in number to that of genes themselves, which are formed as follows: (1) a transcription-termination signal that follows the gene plus (on the complementary strand and located as near to the "anti-gene" as possible); (2) a second termination signal which actively prevents the accidental transcription of the anti-gene. Thus, the adjacent termination-anti-termination region of one strand would complement the anti-termination-termination region of the other.
Submitted on July 28, 1975