EVIDENCE OF PREFERENTIAL PAIRING OF CHROMOSOMES AT MEIOSIS IN ANEUPLOID YEAST

1 Division of Biological Sciences National Research Council of Canada Ottawa, Canada K1A 0R6

Meiotic pairing in homothallic S. cerevisiae was studied by tetrad analysis, using strains that were trisomic or tetrasomic for chromosome I. The disomic segregants of these strains produce tetrasomic spore colonies that can be distinguished by their phenotype. Results indicated the existence of preferential pairing and nonrandom assortment of chromosomes at meiosis I. The frequency of crossing over is apparently normal in at least some regions when non-preferred pairing occurs.

Submitted on July 25, 1974
Revised on November 27, 1974