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CYTOLOGICAL DETECTION OF THE c25H DELETION INVOLVING THE ALBINO (c) LOCUS ON CHROMOSOME 7 IN THE MOUSE
D. A. Miller 1, V. G. Dev 1, R. Tantravahi 1, O. J. Miller 1, M. B. Schiffman 2, R. A. Yates 2, and S. Gluecksohn-Waelsch 2
1 Departments of Human Genetics and Development and Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, N.Y. 10032
2 Department of Genetics, Albert Einstein College of Medicine, Bronx, N.Y. 10461
A deletion of the albino (c) locus on mouse chromosome 7 has been demonstrated using Q- and G-banding methods in a mouse heterozygous for the radiation-induced lethal albino allele, c25H. The deletion, which is thought to be 1–6 cM long, represents about 7.6% of the length of the metaphase chromosome.
Submitted on April 11, 1974
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