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RECIPIENT GENE DUPLICATION DURING GENERALIZED TRANSDUCTION
M. Stodolsky 1
1 Loyola University Stritch School of Medicine, Maywood, Illinois 60153
An Hfr13 
proA-lac deletion recipient, -proA-lac-F-purE+-, has been utilized in a study of the origins of duplications formed during chromosome fragment integration. Among the Pro-Lac+ transductants, some have duplications spanning the F locus. These transductants are, or segregate, strains with F' episomes carrying genes of the duplication. Some of the duplications include purE+, a gene which is not coinherited with lac+ during bacteriophage P1-mediated transduction. Thus recipient genes have been duplicated during recombinant formation. Crossing-over models including replication steps provide a basis for explaining the duplication process.
Revised on June 13, 1974