- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Nicklas, R. B.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Nicklas, R. B.
CHROMOSOME SEGREGATION MECHANISMS
R. Bruce Nicklas 1
1 Department of Zoology, Duke University, Durham, North Carolina 27706
Most aspects of chromosome distribution to the daughter cells in meiosis and mitosis are now understood, at the cellular level. The most striking evidence that the proposed explanation is valid is that it correctly predicts the outcome of experiments on living cells in which the experimenter (1) can determine the distribution of any chosen chromosome to a chosen daughter cell, (2) can induce a mal-orientation, and (3) can stabilize a mal-orientation, causing non-disjunction of a chosen bivalent. Recent reviews of chromosome distribution mechanisms are also considered, in an attempt to clarify the remaining unsolved problems.
This article has been cited by other articles:
 |
|
 |
|
  W. Cui and R. S. Hawley The HhH(2)/NDD Domain of the Drosophila Nod Chromokinesin-like Protein Is Required for Binding to Chromosomes in the Oocyte Nucleus Genetics, December 1, 2005; 171(4): 1823 - 1835. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Harris, C. Orme, J. Kramer, L. Namba, M. Champion, M. J. Palladino, J. Natzle, and R. S. Hawley A Deficiency Screen of the Major Autosomes Identifies a Gene (matrimony) That Is Haplo-insufficient for Achiasmate Segregation in Drosophila Oocytes Genetics, October 1, 2003; 165(2): 637 - 652. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. L. Page and R. S. Hawley Chromosome Choreography: The Meiotic Ballet Science, August 8, 2003; 301(5634): 785 - 789. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Shonn, R. McCarroll, and A. W. Murray Requirement of the Spindle Checkpoint for Proper Chromosome Segregation in Budding Yeast Meiosis Science, July 14, 2000; 289(5477): 300 - 303. [Abstract] [Full Text]
|
|
|
|
 |
|
 H. J.G. Matthies, L. G. Messina, R. Namba, K. J. Greer, M.Y. Walker, and R. S. Hawley Mutations in the {alpha}-Tubulin 67C Gene Specifically Impair Achiasmate Segregation in Drosophila melanogaster J. Cell Biol., December 13, 1999; 147(6): 1137 - 1144. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zalevsky, A. J. MacQueen, J. B. Duffy, K. J. Kemphues, and A. M. Villeneuve Crossing Over During Caenorhabditis elegans Meiosis Requires a Conserved MutS-Based Pathway That Is Partially Dispensable in Budding Yeast Genetics, November 1, 1999; 153(3): 1271 - 1283. [Abstract] [Full Text]
|
|
|
|
|
|
R. LeMaire-Adkins, K. Radke, and P. A. Hunt Lack of Checkpoint Control at the Metaphase/Anaphase Transition: A Mechanism of Meiotic Nondisjunction in Mammalian Females J. Cell Biol., December 29, 1997; 139(7): 1611 - 1619. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. S. Roeder Meiotic chromosomes: it takes two to tango Genes & Dev., October 15, 1997; 11(20): 2600 - 2621. [Full Text] [PDF]
|
|
|
|
|
|
K. S. McKim and R. S. Hawley Chromosomal Control of Meiotic Cell Division Science, December 8, 1995; 270(5242): 1595 - 1601. [Abstract] [PDF]
|
|