DEVELOPMENT IN GENETIC MOSAICS OF ARISTAPEDIA, A HOMOEOTIC MUTANT OF DROSOPHILA MELANOGASTER

J. H. Postlethwait ¹ and J. R. Girton ¹

¹ Department of Biology, University of Oregon, Eugene, Oregon 97403

Development of the homoeotic mutation, aristapedia (ss^a), was investigated by means of genetic mosaics. The wild-type alleles of aristapedia and the bristle markers yellow, singed, and forked were removed from cells at different times in development by X-ray induced somatic crossing-over. The phenotype of the resulting clones was examined in order to ascertain whether it was leg or antenna. The y sn f; ss^a clones showed a leg phenotype if induced before the mid-third instar, but showed an antennal phenotype if induced after this time. Late non-expression of ss^a may be due either to an influence of surrounding ss⁺ tissues on the small ss^a clones, or to a persistence of the effect of ss⁺ for one or two cell generations after it is removed from a cell line.

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