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GENETIC ANALYSIS OF THE ACTIVE SITES OF lac REPRESSOR
Magnus Pfahl 1, Christel Stockter 1, and Bruno Gronenborn 1
1 Institut für Genetik der Universität zu Köln, 5 Köln 41, Weyertal 121, West Germany
Selection methods for the isolation of i–d and is mutants are described. Two hundred and forty-seven i–d and 98 is mutations have been localized by deletion mapping. All i–d mutations map in the region of the i gene, which codes for the aminoterminal part of the lac repressor, whereas is mutations map in the middle of the i gene and at the proximal end of the i–d cluster.
Submitted on October 1, 1973
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