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- Articles by Gelbart, W. M.
A NEW MUTANT CONTROLLING MITOTIC CHROMOSOME DISJUNCTION IN DROSOPHILA MELANOGASTER
William M. Gelbart 1
1 Division of Biology, California Institute of Technology, Pasadena, California 91109
A new mutant, mit (mitotic loss inducer), is described. The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females. Mosaic loss of maternal or paternal chromosomes can occur. The probabilities of either maternal or paternal X chromosome loss are equal. mit has been mapped to approximately 57 on the standard X chromosome map.Using gyandromorphs generated by mit, a morphogenetic fate map, placing the origins of 40 cuticular structures on the blastoderm surface, has been constructed. This fate map is consistent with embryological data and with the two other fate maps generated in different ways.
Submitted on July 2, 1973