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NINETEEN PARACENTRIC CHROMOSOMAL INVERSIONS IN MICE
Thomas H. Roderick 1 and Norman L. Hawes 1
1 The Jackson Laboratory, Bar Harbor, Maine 04609
Using mutagens on sperm and spermatids we have produced nineteen chromosomal inversions in mice. The levels of radiation and chemical mutagen we used induced inversions in about one per cent of the animals screened. Nine inversions have been transmitted through successive generations, and the particular frequency of first meiotic anaphase bridges manifested by each inversion remained constant. The cytological properties of first meiotic anaphases varied considerably among the inversions. Chromosomal locations of five inversions are known. Four of the five are fully viable in homozygous condition.
Submitted on July 6, 1973
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