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THE ANALYSIS OF QUANTITATIVE TRAITS FOR SIMPLE GENETIC MODELS FROM PARENTAL, F1 AND BACKCROSS DATA
R. C. Elston 1 and John Stewart 2
1 Department of Biostatistics, Genetics Curriculum, and the Biological Sciences Research Center, U.N.C., Chapel Hill, N. C. 27514
2 Department of Genetics, Cambridge University
The following models are considered for the genetic determination of quantitative traits: segregation at one locus, at two linked loci, at any number of equal and additive unlinked loci, and at one major locus and an indefinite number of equal and additive loci. In each case an appropriate likelihood is given for data on parental, F1 and backcross individuals, assuming that the environmental variation is normally distributed. Methods of testing and comparing the various models are presented, and methods are suggested for the simultaneous analysis of two or more traits.
Submitted on May 4, 1971Revised on November 8, 1972
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