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REPAIR OF UV-INDUCED PYRIMIDINE DIMERS IN DROSOPHILA MELANOGASTER CELLS IN VITRO
James E. Trosko 1 and Kathy Wilder 1
1 Department of Human Development, Michigan State University, East Lansing, Michigan 48823
Tissue culture cells of Drosophila melanogaster were given various doses of ultraviolet light. The results indicate that Drosophila cells do have a dark-repair excision mechanism which is not sensitive to caffeine. Pyrimidine dimers were destroyed by photoreactivating illumination in these cells and this destruction probably represents monomerization of the pyrimidine dimers.
Submitted on August 24, 1972Revised on October 25, 1972