A DOMINANT CONSTITUTIVE phoR MUTATION IN ESCHERICHIA COLI

1 Department of Genetics, University of Washington, Seattle, Washington

A dominant constitutive mutation of the phoR locus controlling alkaline phosphatase synthesis in Escherichia coli is described. Its phenotype can be explained by the production of a poisonous subunit of the phoR gene product. The phoR gene product is inferred to consist of at least 3 or 4 subunits.

Submitted on June 5, 1972