CLONAL VARIATION IN PARAMECIUM II. A COMPARISON OF STABLE AND UNSTABLE CLONES OF THE SAME SEROTYPE

1 Department of Biology, Haverford College, Haverford, Pennsylvania 19041

Paramecium generally expresses only one antigen on its surface from among an array of antigens. This mutual exclusion of antigens now has been shown in certain instances to be illusory. Unstable clones which will give rise to subclones with new serotypes possess several antigens. Unstable clones, even though they manifest only one serotype, continually manufacture an antigen other than the surface antigen characteristic of the serotype.

Submitted on November 16, 1971
Revised on March 3, 1972