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INTERACTIONS BETWEEN COLICINOGENIC FACTOR B AND F-TYPE FACTORS: ISOLATION OF A MUTANT F-lac FACTOR INSENSITIVE TO THE EFFECT OF COLICINOGENIC FACTOR B
T. Negrotti 1 and R. Nagel de Zwaig 1
1 Departamento de Biología Celular, Facultad de Ciencias, U.C.V., Caracas, Venezuela
An extrachromosomal factor, colicinogenic factor B (colB) inhibits expression of fertility functions of various F-type factors in strains of E. coli K12. Mutant F-lac factors simultaneously became insensitive to all the effects of colB as well as to similar actions exerted by a resistance transfer factor, R fi+. This suggests that a common site or activity necessary for the expression of several F functions is affected by products of both colB and R fi+.
Submitted on August 11, 1971Revised on October 19, 1971