- THIS ARTICLE
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
genetics.108.092460v1
181/1/341 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Wakeley, J.
- Articles by Sargsyan, O.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Wakeley, J.
- Articles by Sargsyan, O.
Originally published as Genetics Published Articles Ahead of Print on November 10, 2008.
Genetics, Vol. 181, 341-345, January 2009, Copyright © 2009
doi:10.1534/genetics.108.092460
Extensions of the Coalescent Effective Population Size
John Wakeley1 and Ori Sargsyan
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138
1 Corresponding author: 4100 Biological Laboratories, 16 Divinity Ave., Cambridge, MA 02138.
E-mail: wakeley{at}fas.harvard.edu
We suggest two extensions of the coalescent effective population size of SJÖDIN et al. (2005) and make a third, practical point. First, to bolster its relevance to data and allow comparisons between models, the coalescent effective size should be recast as a kind of mutation effective size. Second, the requirement that the coalescent effective population size must depend linearly on the actual population size should be lifted. Third, even if the coalescent effective population size does not exist in the mathematical sense, it may be difficult to reject Kingman's coalescent using genetic data.
 |