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Originally published as Genetics Published Articles Ahead of Print on August 30, 2008.
Genetics, Vol. 180, 669-672, September 2008, Copyright © 2008
doi:10.1534/genetics.108.090035
Sex Change by Gene Conversion in a Caenorhabditis elegans fog-2 Mutant
Vaishali Katju, Elisa M. LaBeau, Kendra J. Lipinski and Ulfar Bergthorsson1
Department of Biology, University of New Mexico, Albuquerque, New Mexico 87131
1 Corresponding author: Department of Biology, MSC03 2020 1 University of New Mexico, Albuquerque, NM 87131-0001.
E-mail: ulfar{at}unm.edu
Caenorhabditis elegans primarily reproduces as a hermaphrodite. Independent gene conversion events in mutant obligately outcrossing populations of C. elegans [fog-2(lf)] spontaneously repaired the loss-of-function mutation in the fog-2 locus, thereby reestablishing hermaphroditism as the primary means of reproduction for the populations.
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