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Genetics, Vol. 179, 701-704, May 2008, Copyright © 2008
doi:10.1534/genetics.108.086918
On the "NPD Ratio" as a Test for Crossover Interference
Franklin W. Stahl1
Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403
1 Address for correspondence: Institute of Molecular Biology, 1229, University of Oregon, Eugene, OR 97403-1229.
E-mail: fstahl{at}uoregon.edu
The "NPD ratio," widely used by yeast geneticists, is of limited applicability and is prone to falsely indicate significant crossover interference in a chi-square test. A simple, better chi-square test for interference in two-factor crosses is described.
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Genetics 2008 179: NP.