Originally published as Genetics Published Articles Ahead of Print on October 18, 2007.

Genetics, Vol. 177, 1951-1953, November 2007, Copyright © 2007
doi:10.1534/genetics.107.079368

Ninety-Six Haploid Yeast Strains With Individual Disruptions of Open Reading Frames Between YOR097C and YOR192C, Constructed for the Saccharomyces Genome Deletion Project, Have an Additional Mutation in the Mismatch Repair Gene MSH3

Kevin R. Lehner^*,, Megan M. Stone, Rosann A. Farber^, and Thomas D. Petes^*,1

^* Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, Department of Pathology and Laboratory Medicine and Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599-7525

¹ Corresponding author: Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710.
E-mail: tom.petes{at}duke.edu

As part of the Saccharomyces Genome Deletion Project, sets of presumably isogenic haploid and diploid strains that differed only by single gene deletions were constructed. We found that one set of 96 strains (containing deletions of ORFs located between YOR097C and YOR192C) in the collection, which was derived from the haploid BY4741, has an additional mutation in the MSH3 mismatch repair gene.

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